生物通

谷物麸皮中阿魏酸(FA)通过双重调控XOD/尿酸转运体改善高尿酸血症的 ...

针对高尿酸血症治疗中天然XOD（黄嘌呤氧化酶）抑制剂筛选效率低、机制研究不深入的问题，研究人员通过建立"抗氧化-酶抑制-化学表征"三级筛选体系，发现玉米麸皮结合态酚类（IC50 ABTS 0.23 μg/mL）中FA（阿魏酸）具有最强XOD抑制活性（86.7%），并通过动物实验 ...
生物通

冬瓜皮(BE)通过调控XOD/URAT1/GLUT9/ABCG2/OAT1通路及TLR4/NF-κB/NLRP3信号轴 ...

本研究针对高尿酸血症(HUA)及其并发症的防治需求，揭示了传统中药冬瓜皮(Benincasae Exocarpium, BE)通过抑制黄嘌呤氧化酶(XOD)活性 ...
Nature

Discovery, Characterization, and Anti-XOD Activity of Calcium Metallophore from Coix ...

The Nature Index 2025 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their output in ...