Comparative genomic hybridization (CGH) is a technique that has greatly facilitated detection of gains and losses in DNA copy number, and has been of particular utility in elucidating the pattern of ...

The introduction of array comparative genome hybridization (CGH) into prenatal genetic diagnosis presents both challenges and controversy to the clinical cytogenetic community. The challenges are ...

为探究儿童急性淋巴细胞白血病（ALL）的发病机制，研究人员对 67 例马来西亚正常核型的儿童 ALL 患者开展基于阵列比较基因组杂交（array-CGH）研究。结果发现了致病性拷贝数变异（CNVs）和意义不明变异（VUS），这有助于白血病分类和个性化治疗123。 儿童急性 ...

infoQuant Ltd brings microarray technology closer to clinical use with its latest release of copy number analysis and interpretation software "oneClickCGH" and "CGH Fusion" for microarray-based ...

Roche NimbleGen, Inc. has launched NimbleGen Comparative Genomic Hybridization (CGH) microarrays in a 12x135K format for analysis of DNA copy number variation. NimbleGen CGH 12x135K arrays will allow ...

Comparative genomic hybridization (CHG) provides the densest coverage of probes for CNV detection, but the traditional technique using bacterial artificial chromosome arrays is time consuming and not ...

Early efforts to examine genomic changes in the clinical setting relied on cytogenetic techniques such as chromosome karyotyping, a widely used approach to examine chromosomes and identify changes ...

SANTA CLARA, Calif.--(BUSINESS WIRE)--Agilent Technologies Inc. (NYSE:A) today announced that scientists using the company’s comparative genomic hybridization (CGH) technology have shown that cancer ...

BRAF V600E mutations in benign and malignant peripheral nerve sheath tumors. Background: Gain or loss of chromosome arms are frequently detected in gastrointestinal stromal tumors (GISTs), and have ...

Due to its higher resolution, oligo array CGH has recently made strong inroads in the cytogenetic lab. It’s not surprising. With an increased sensitivity of more than 1,000-fold, microarrays can ...

Microarray based comparative genomic hybridisation (array CGH) is a new technology with uses developing in various diagnostic areas within the NHS. One important context is the investigation of ...