A large number of drug-induced long QT syndromes are ascribed to blockage of hERG potassium channels. The aim of this study was to construct novel computational models to predict compounds blocking ...

ABSTRACT: Zooplankton play a critical role in aquatic ecosystems and are commonly used as bioindicators to assess anthropogenic and climate impacts. Nevertheless, traditional microscope-based ...

We propose new nonparametric empirical Bayes methods for high-dimensional classification. Our classifiers are designed to approximate the Bayes classifier in a hypothesized hierarchical model, where ...